skip to main content
Untitled Page
PLCO Announcements
Preliminary applications are now being accepted for PLCO EEMS Round 21 and for Funding Opportunity Announcement (PAR-15-297). For more information please visit

The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a large population based randomized trial designed and sponsored by the National Cancer Institute (NCI) to determine the effects of screening on cancer-related mortality and secondary endpoints in men and women aged 55 to 74. The screening component of the trial was completed in 2006. Participants are being followed and additional data will be collected through 2015. Numerous epidemiologic and ancillary studies are also underway to answer related crucial questions.

Learn more about PLCO, how to obtain access to study data and biospecimens, and view additional information by accessing links below. Go to PLCO STaRS to complete and submit all forms and applications for biospecimen requests. Access PLCO STaRS by clicking the login button located on the upper right corner of this page.

If you do not have access to the PLCO STaRS site or have questions, contact the PLCO Helpdesk at

Public use datasets can be found at the Cancer Data Access System (CDAS).

Data & Biospecimen

Propose a Study

Current & Completed Research

How Do I?

Investigators who are interested in learning more about PLCO biospecimens or data can find more information in the following sections:


The following links provide investigators with information on how to submit an application, sample forms, and Etiologic & Early Marker Studies (EEMS) access policies and procedures:


Data Only


Investigators who are interested in ongoing research or published manuscripts will find information in the following links:


Page last updated November 30, 2012